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10.2147/VMRR.S408352 [DOI] [PMC free article] [PubMed] [Google Scholar] 27.Ludwig BS, Kessler H, Kossatz S, Reuning U (2021) RGD-binding integrins revisited: how recently discovered functions and novel synthetic ligands (re-)shape an ever-evolving field
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First Study The first poster, entitled, “Pre-clinical Proof-of-concept of Anti-fibrotic Activity of Caveolin-1 Scaffolding Domain Peptide LTI-03 in Ex Vivo Precision Cut Lung Slices (PCLS) from Patients with Idiopathic Pulmonary Fibrosis,” evaluates the antifibrotic effects of LTI-03, Rein’s novel, multi-pathway, Caveolin-1 (Cav1)-related peptide currently in a Phase 2 trial for the treatment of IPF, and of nintedanib, a current standard of care treatment for IPF, in PCLS from 12 patients with end-stage disease